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    Vol 1(1), 2014
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  • Know Res., 2014, 1(1),  pp 68-78  

    DOI:10.7598/kor2014.122

    Review Article

    Review on Psychopharmacological Activities of Substituted Triazole Analogues

  • Mohammad Asif
  • Department of Pharmacy, Guru Ram Das (PG) IMT, Dehradun, (Uttarakhand), 248009, India
  • Abstract

    Triazoles and its derivatives possess a great importance in medicinal chemistry and can be used for the synthesis of numerous heterocyclic compounds with different biological activities. In the last few decades, the chemistry of triazoles and their fused heterocyclic derivatives has received considerable attention owing to their synthetic and effective biological activities such as antinflammatory, analeptic, sedatives, antianxiety, antidepressant, antimicrobial etc. Also, there are known drugs in market containing the triazole group such as triazolam, alprazolam, etizolam, furacylin, fluconazole, intraconazole, voriconazole. This review covers the latest information over active triazoles derivatives having different pharmacological action on central nervous system. Thus triazole acts as a promising medicinal agent for the scientists working over this field. This review can be helpful to develop various more new compounds possessing triazoles moiety that could be better in terms of efficacy and lesser toxicity.

    Keywords

    Triazole, anticonvulsant, anti-depressant, biologi

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